Assistant Professor Dr. Baskaran Gunasekaran

Assistant Professor Dr. Baskaran Gunasekaran

Assistant Professor | Department of Biotechnology
 

Academic Qualifications

PhD Biochemistry
MSc Biochemistry
BSc (Hons) Biochemistry

Areas of Interest
Enzyme Biochemistry
Phytochemistry and alternative medicine
Biosensor and Bioremediation
Research

Research Grants

  1. Name of grant: Innohub grant
    Funder: UPM
    Project Title: Bone scaffolding for bone repair using cockle shells
    Code: - 
    Duration: 2013 - 2014
    Role: PI
    Amount: RM 100,000
    Status: Completed
  2. Name of grant: Public-Private Research Network (PPRN) 
    Funder: MOHE
    Project Title: Improvement on structure and mechanical strength of bone scaffold
    Code: - 
    Duration: 2015 - 2016
    Role: PI
    Amount: RM 50,000
    Status: Completed
  3. Name of grant: Pioneer Scientist Innovative Fund (PSIF) 
    Funder: UCSI University
    Project Title: Effects of drying techniques on antioxidant and anti-inflammatory properties of Basella alba
    Code: - 
    Duration: 2018 - 2019
    Role: PI
    Amount: RM 25,000
    Status: On-going
  4. Name of grant: Fundamental Research Grant Scheme (FRGS)
    Funder: MOE
    Project Title: Comprehending the structural interaction between bacterial leukotoxin (LtxA) and human leukocyte
    Code: - 
    Duration: 2019 - 2021
    Role: Co-PI
    Amount: RM 167,000
    Status: On-going
  5. Name of grant: Biotropics Industry Grant
    Funder: Biotropics Sdn Bhd
    Project Title: Eurycoma longifolia extract and its use in enhancing male reproductive system
    Code: - 
    Duration: 2019 - 2020
    Role: PI
    Amount: RM 50,000
    Status: On-going

Current Research Project

  1. Novel compound (AAG) for use as medicament for treatment of hypercholesterolemia and atherosclerosis 
  2. Phytochemical profiling and pathway analysis of global gene expression change in cell line induced by Basella alba extract
  3. Isolation of enzyme for the degradation of plastic polymers
  4. Screening the antiviral activity of medicinal plants against EMS in shrimps
  5. Isolation and characterization of peptide from Eurycoma longifolia extract for testosterone enhancement
  6. In vitro inhibitory potential of Amaranthus viridis against key enzymes for diabetes

 

Publications

Selected Journal Articles

  1. Baskaran Gunasekaran, Noor Azlina Masdor, Mohd Arif Syed, and Mohd Yunus Shukor (2013). An inhibitive enzyme assay to detect mercury and zinc using protease from Coriandrum sativum, The Scientific World Journal, 678356 
  2. Baskaran Gunasekaran, Noor Azmi Shaharuddin and Mohd Yunus Shukor (2014). Anti-atherosclerotic effects of plant flavonoids, BioMed Research International Journal, 480258
  3. Baskaran Gunasekaran, Shamala Salvamani, Noor Azmi Shaharuddin, Aqlima Ahmad, Parveen Devi Pattiram and Mohd Yunus Shukor (2015). HMG-CoA reductase inhibitory activity and phytocomponent investigation of Basella alba leaf extract as a treatment for hypercholesterolemia, Drug Design, Development & Therapy, vol. 2015, 509-517 (
  4. Baskaran, Gunasekaran, Azrina Azlan, Siti Aqlima Ahmad, Swee Keong Yeap and Mohd Yunus Shukor (2015). Hypocholesterolemic and antioxidant effects of Basella alba inhibit atherosclerosis in hypercholesterolemia-induced rabbits, Evidence-Based Complementary & Alternative Medicine, Article ID 751714
  5. Shamala Salvamani, Baskaran Gunasekaran, Mohd Yunus Shukor, Noor Azmi Shaharuddin, Mohd Khalizan Sabullah and Siti Aqlima Ahmad (2016). Anti-HMG-CoA reductase, antioxidant and anti- inflammatory activities of Amaranthus viridis leaf extract as a potential treatment for hypercholesterolemia, Evidence-Based Complementary & Alternative Medicine, Article ID 8090841
  6. Shamala Salvamani, Baskaran Gunasekaran, Mohd Yunus Shukor, Md. Zuki Abu Bakar, Siti Aqlima Ahmad (2016). Phytochemicals investigation, hypocholesterolemic and anti-atherosclerotic effects of Amaranthus viridis leaf extract in hypercholesterolemia-induced rabbits, RSC Advances, 6, 32685-32696
  7. Mohd Khalizan Sabullah, Jualang Azlan Gansau, Hartinie Marbawi, Ainol Azifa Mohd Faik, Suraya Abdul Sani1, Rahmath Abdulla, Siti Aqlima Ahmad, Mohd Yunus Shukor and Baskaran Gunasekaran (2018). Potential use of Acetylcholinesterase from Osteochilus hasselti in Monitoring Heavy Metal Pollution in Malaysia River, ASM Science Journal, 11, Special Issue 2, 2018 for SANREM, 225-234
  8. Thayaalini Subramaniam, Yam Hok Chai, Shamala Salvamani and Baskaran Gunasekaran (2018). Preliminary Assessment of Herbal Remedies in Inhibiting Citrullination of Arginine: An Implication in Mitigating Rheumatoid Arthritis, American Journal of Bio-pharmacology Biochemistry and Life Sciences, Vol. 6: OP13 (conference proceeding)
  9. Sook-Chin Chew, Choon-Hui Tan, Liew-Phing Pui, Pei-Nee Chong, Baskaran Gunasekaran and Nyam Kar Lin (2019). Encapsulation Technologies: A Tool for Functional Foods Development, International Journal of Innovative Technology and Exploring Engineering (IJITEE) ISSN: 2278-3075, Volume-8 Issue-5S
  10. Baskaran, AK Muhammaddul Qawiy and Mohammad Taha (2019). An Inhibitive Method to Determine Heavy Metals using A Cysteine Protease Ficin, International Journal of Innovative Technology and Exploring Engineering (IJITEE) ISSN: 2278-3075, Volume-8 Issue-5S

Patent

  1. Mohd Yunus Shukor, Baskaran Gunasekaran, Shamala Salvamani, Azrina Azlan, Md Zuki Abu Bakar and Siti Aqlima Ahmad. Novel compound for use as medicament for treatment of hypercholesterolemia and atherosclerosis (Patent file-PI 2014704025). 

Conferences

  1. Shamala Salvamani & Baskaran Gunasekaran (2019). Hypocholesterolemic and anti-atherosclerotic effects of Amaranthus viridis leaf extract in hypercholesterolemia-induced rabbits, International Conference for Molecular Biology and Biotechnology (ICMBB), UCSI University Kuala Lumpur, 24th April 2019.
  2. Panel for Sustainability Summit Asia 2018, Sunway Resort Hotel & Spa, Sunway City Kuala Lumpur, 15th November 2018.
  3. Thayaalini Subramaniam, Yam Hok Chai, Shamala Salvamani and Baskaran Gunasekaran (2018). Preliminary assessment of herbal remedies in inhibiting citrullination of arginine: an implication in mitigating Rheumatoid Arthritis, International Conference on Recent Trends in Humanities & Science, UTAR Kampar, Perak.
  4. Baskaran Gunasekaran, Shamala Salvamani, Noor Azmi Shaharuddin, Aqlima Ahmad, Parveen Devi Pattiram and Mohd Yunus Shukor (2015). HMG-CoA reductase inhibitory activity and phytocomponent investigation of Basella alba leaf extract as a treatment for hypercholesterolemia, International Conference on Science, Technology, Engineering and Management, Jeppiaar Engineering College, Chennai, India.
  5. Baskaran Gunasekaran, Noor Azmi Shaharuddin, Azrina Azlan, Noordin Mohamed Mustapha, Mohd Yunus Shukor (2014). Anti cholesterolemic effects of Basella alba inhibits atherosclerosis in hypercholesterolemia-induced rabbits, Monash University Science Symposium.
  6. Baskaran Gunasekaran, Noor Azmi Shaharuddin, Azrina Azlan, Noordin Mohamed Mustapha, Mohd Yunus Shukor (2013). The inhibitory effect of some Malaysian plant extracts on the 3-Hydroxy-3-Methyl glutaryl Coenzyme A Reductase, 38th Annual Conference of Malaysian Society for Biochemistry & Molecular Biology.
  7. Baskaran Gunasekaran and Mohd Yunus Shukor (2010). Herbs as potential medicine for diseases. 3rd World Conference on Siddhar Principles, Malaysian Society of Agastiyar.
  8. Baskaran Gunasekaran, Mohd Arif Syed and Mohd Yunus Shukor (2008). Detection of heavy metals using protease from Ficin, Regional Conference on Biosensor and Biodiagnostics.

Awards and Recognitions

  1. Platinum Award-British Invention Show (BIS). Alexandria Palace, London, 13-16th October, 2011.
  2. Gold medal- British Invention Show (BIS). Alexandria Palace, London, 13-16th October, 2011.
  3. PhD Distinction Award, Universiti Putra Malaysia, 2015
  4. Gold medal-Pameran Rekacipta Penyelidikan dan Inovasi, 2016
  5. Young Scientist Award- International Research Foundation, India

Contributions to Society

  1. Speaker in Technology Preview Pitch, BioMalaysia, 17th August 2015
  2. Speaker in SMK Seri Permata Kuala Lumper, representing UCSI University, 21st March 2017
  3. Speaker in Astro Vanavil-vizthugal TV program, 4th January 2018
  4. Every Child is a scientist Program (ECSP)
  5. Reviewer for Science Malaysiana Journal
  6. Reviewer for Biomed International Journal
  7. Reviewer for Evidence Based and Complimentary Medicine Journal

Networks and Collaborations on Research

  1. The Centre for Drug Research, USM
  2. Natural Product Lab, IBS, UPM
  3. Bioremediation lab, UPM
  4. NARA institute of Science and Technology, Japan
  5. Agro-Biotech Institute Malaysia
  6. Malaysian Genome Institute
  7. International Medical University

Professional Affliation

  1. Member of Malaysian Society for Biochemistry and Molecular Biology (MSBMB)
  2. Member of Malaysian Society of Molecular Biology and Biotechnology (MSMBB)
  3. Young Scientists Network-Academy of Sciences Malaysia (YSN-ASM)
  4. Member of Malaysia Natural Product Society 
  5. Member of Malaysian Wellness Society