Clinical Associate Professor Dr Edmond Ng Siah Chye
Clinical Associate Professor | School of Healthy Aging, Aesthetic and Regenerative Medicine
Academic Qualifications
Master in Anti Aging, Regenerative & Aesthetic Medicine
Doctor of Medicine
Diploma in Aesthetic Medicine
Certificate in Aesthetic Medicine
Areas of Interest
Aesthetic medicine
Regenerative Medicine
Complementary and Alternative Medicine
Public Health
Research
Research Area
- As a medical doctor with special interested in Aesthetic Medicine, my primary research interests revolve around understanding the role Aesthetic Medicine and Regenerative medicine that contribute to human health and disease, and applying that information to improve human wellbeing.
- Mechanisms that influence the rejuvenation of skin cells:I am interested in the molecular mechanisms of skin aging which is essential to identify new therapeutic targets and develop new agents, with a particular emphasis on the topical modalities. Also, identifying pathways involved in delaying skin aging in response to external stimuli.
Research Grants
- Name of grants: Research Excellence and Innovation Grant (REIG)
Funder: REIG-FMS-2020/044
Project title: Effect of Pharmacological inhibitors of HIPPO pathway in COL1A1 synthesis and fibroblast aging
Code: REIG-FMS-2020/044
Duration: 2020- 2022
Role: Co- Investigator
Amount: RM 50,000
Status: On-going
Current Research Project
- EVALUATE THE SAFETY (AND EFFICACY) OF SKINCARE PRODUCT USING BIOACTIVE COMPOUNDS SECRETED BY DERMAL FIBROBLASTS IN THE REDUCTION OF SIGNS OF FACIAL AGING A NON-RANDOMIZED CONTROLLED STUDY.
- Pharmaceutical Formulation of a drug based on Molecular study of Synergetic inhibiting effects of PARP inhibitor and Calcitriol in selected TNBC cell lines.
Publications (Selected)
- A Pilot Randomized Controlled Trial (RCT) Evaluating the Efficacy of an Exosome-Containing Plant Extract Formulation for Treating Male Alopecia. Life. 2025; 15, 500 https://doi.org/10.3390/life15030500
- Efficacy, Safety, Satisfaction, Adherence to Treatment with Nano-Formulated Cysteamine Tranexamic Acid Cream to Treat Melasma. J Drugs Dermatol. 2024;23(7):529-537, doi:10.36849/JDD.7765R1
- Fast food consumption, obesity and nutrient intake among adults in Indonesia. Food Research. 2024; 8 (Suppl. 3) : 55 – 65
- Combination of Talazoparib and Calcitriol Enhanced Anticancer Effect in Triple−Negative Breast Cancer Cell Lines. Pharmaceuticals 2022, 15, 1075. https://doi.org/ 10.3390/ph15091075
- Effect of Rice (Oryza sativa L.) Ceramides Supplementation on Improving Skin Barrier Functions and Depigmentation: An Open-Label Prospective Study. Nutrients, 14(13). doi:10.3390/nu14132737
- Awareness and perception of medical genetic services among Malaysian parents of autism spectrum disorders children: the lessons to be learned, Advances in Autism, Vol Vol. 8 No. 1, pp. 27-38. https://doi.org/10.1108/AIA-08-2020-0047
- Polymorphisms in P53 and VEGFA genes in different types of periorbital hyperpigmentation in a Malaysian Chinese population. Australas J Dermatol. 2018 Sep 14. doi: 10.1111/ajd.12918.
Conference
- Ng Chiat Yin, Farahnaz Amini , Normina Ahmad Bustami, Eugenie Tan Sin Sing, Razinah Sharif , Edmond Ng Siah Chye. Association of Physical Activity and DNA Damage Among Malay Women. The International Sport, Health and Emerging Technologies Summit Conference (iSHE-SC 2021). Online Conference, Malaysia, 27-29 October 2021
- Sharmanee Thiagarajah, Effiong P. E., Siyumbwa S. N., Eugenie Sin Sing Tan, Chung Keat Tan, Farahnaz Amini, Normina Bustami, Edmond Siah Chye Ng (2021). Antimicrobial Effect of Quercus Infectoria and Acorus Calamus in Wound Model. 4th International Conference on Molecular Biology & Biotechnology (ICMBB), 1st-3rd June 2021, page 137
- Eugenie Sin Sing Tan, Yu Bin Ho, Chung Keat Tan, Farahnaz Amini, Normina Bustami, Sharmanee Thiagarajah, Edmond Siah Chye Ng (2021). Pharmaceuticals and Personal Care Products (PPCPs) Residues in Surface Water Bodies from Selangor (Malaysia): Occurrence and Environmental Risk Assessment. 4th International Conference on Molecular Biology & Biotechnology (ICMBB), 1st-3rd June 2021, page 162
- Ng CY., Seghayat MS., Normina AB., Tan ESS., Tan CK., Sharmanee T., Ng ESC., Amini F. Cluster analysis of macronutrient intake and DNA damage among Malay Women. 35th Annual Scientific Conference, 24 to 25 Nov 2020, Kuala Lumpur Malaysia.
- Amini F., Mohini, C.,Seghayat MS, , Ng ESC. Public health concerns: Knowledge and awareness of modifiable CVD risk factors in Kuala Lumpur. European Public Health Conference 2018. 28th Nov to 1st Dec 2018. Ljubljana Slovenia
- Wong FH, Amini, F, Ng ESC. 2020. Synergic effect of vitamin D supplementation and PARP Inhibitors on TNBC cell line proliferation. Together Towards Optimal Nutrition. NSM Conference 2020. Kuala Lumpur, Malaysia
Networks and Collaborations on Research
- Malaysian industry partners
- Medical, pharmaceutical and cosmeceutical companies
- Multidisciplinary collaborations across medicine, public health, environmental health and precision medicine
Contributions to Society
- Medical & scientific consultant for healthcare industries
- Public health education and community outreach
- Organiser of international conferences, CME programmes and research workshops
Awards and Recognition
- International Conferences & Industrial Awards: 18
- National Research Grants: 3
- Copyrights: 19
Professional Bodies
- Malaysian Medical Association (MMA)
- Malaysian Society of Aesthetic Medicine (MSAM)
- Medical Practitioners Coalition Association of Malaysia (MPCAM)
- Pertubuhan Doktor Estetik Berdaftar Malaysia (PDEBM)
