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Dr. Malarvili A/P Selvaraja
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Assistant Professor Dr Malarvili A/P Selvaraja

Assistant Professor | Department of Pharmaceutical Biology

Academic Qualifications

PhD in Immunobiology
Master in Science (Physiology)
BSc in Biotechnology

Areas of Interest
Immunology
Autoimmunity
Immunopharmacology
Antimicrobial resistance
Anti-cancer
Research

 

Current research project (PI/Co-PI)

Grants

Collaboration

Status

Uterine Fibroid Effect and the Mechanism of Action of TC-16 Polyherbal Formulation in Human Uterine Leiomyoma Cell Line. (PI)

UCSI Internal REIG Grant &

Department of Pathology, Universiti Putra Malaysia.

Completed.

Integrative Elucidation of Socio-Ecological Drivers of Antimicrobial Resistance Emergence and Transmission at the Human Animal Environment Interface. (PI)

FRGS

University Kebangsaan Malaysia Monash University Malaysia

On-going

In vitro and in vivo evaluation of the ameliorative effect of standardized TC-16 polyherbal formulation in murine uterine fibroid and dysmenorrhea model. (Co-PI)

UCSI Internal REIG Grant &

 

On-going

Investigating the synergistic effects involved for 5- fluorouracil in combination with Deguelin on Colorectal Cancer in in-vitro and in-vivo models and its underlying mechanism of action. (PI)

UCSI Internal REIG Grant

Universiti Putra Malaysia Monash University Australia. Universiti Malaya.

On-going

The investigation of 7-Benzoylnimbocinol isolated from Azadirachta Indica on Endoplasmic Reticulum (ER) Stress. (Co-PI)

UCSI Internal REIG Grant On-going

 

PhD students (Current)

Huang Feng

 

Master students (Current)

Sasikumar A/L Murthi (Co-supervisor)

 

Undergraduate students (Current)

Chong Kar Jing (2024)

 

Undergraduate students (Completed)

Lum Xiao Herng (2023)

Tammy Ng Yoon Hwei (2023)

Alfarizzi Ramadhan Bin Hendra (2023)

 

Publications

  1. Fatokun, O., Magunga, B. T., Oranye, N., & Selvaraja, M. (2024). Public awareness, risk perceptions and behaviour towards antibiotic use in food-producing animals and antimicrobial resistance in Malaysia: A cross-sectional study. Preventive Veterinary Medicine, 228, 106224.
  2. Mochamad, L., Malarvili, S., Jasmine, K., & Lim, V. (2024). In vitro analysis of quercetin-like compounds from mistletoe Dendrophthoe pentandra (L.) Miq as a potential antiviral agent for Newcastle disease. F1000Research, 12(1214), 1214.
  3. Huang, F., Alshehade, S. A., Zhao, W. G., Li, Z. Y., Fong, J. Y., Okechukwu, P. N., ... & Selvaraja, M.* (2024). Bioinformatics mining and experimental validation of prognostic biomarkers in colorectal cancer.
  4. Morak-Młodawska, B., Martula, E., Jeleń, M., Okechukwu, P. N., Feng, H., & Selvaraja, M. (2024). New Dimers of Dipyridothiazines with Anticancer Activities. Malaysian Journal of Medicine & Health Sciences, 20.
  5. Feng, H., Lakshmi, K. V., Ng, C. T., Sasikumar, M., Arip, M., Hassan, M., ... & Selvaraja, M.* (2023). Update on Remdesivir in the Treatment of Novel Coronavirus Pneumonia. Progress In Microbes & Molecular Biology, 6(1).
  6. Kumar, D., Dey, Y. N., Pramanik, S. D., Singh, L. P., Selvaraja, M., & Rajagopal, M. (2023). Potential of Hesperidin in the Medicinal Field. Current Bioactive Compounds, 19(5), 17-25.
  7. Tan, L. F., Yap, V. L., Rajagopal, M., Selvaraja, M., Leong, M. Y., & Tan, P. L. (2023). Phytochemical Screening and Evaluation of Antioxidant Interaction in A New Polyherbal Formulation TC-16: When 1+ 1≠ 2. Current Trends in Biotechnology & Pharmacy, 17.
  8. Yap, V. L., Rajagopal, M., Selvaraja, M., Arip, M., Kumar, D., & Chinnappan, S. (2023). Medicinal Herbs for Uterine Fibroids: A Mechanistic Review. Current Trends in Biotechnology & Pharmacy, 17.
  9. Loh, P. Y., Rajagopal, M., Selvaraja, M., Yap, V. L., & Tan, L. F. (2023). Antioxidant Potential of a Novel Polyherbal Formulation: DM-15. Current Trends in Biotechnology & Pharmacy, 17.
  10. Tan, L. F., Rajagopal, M., & Selvaraja, M. (2023). An Overview on the Pathogenesis of Cervical Cancer. Current Trends in Biotechnology and Pharmacy, 17(1), 717-734.
  11. Sulaiman, M., Zarubaev, V., Samudi, C., Rahmatullah, M., Jannat, K., Paul, A., Selvaraja, M. ... & Wiart, C. (2022). Natural products from medicinal plants in Asia and the Pacific for RNA viruses: Hercules’ fifth labour. Pharmaceutical Biology, 60(1), 2049-2087.
  12. Tan, L. F., Yap, V. L., Rajagopal, M., Wiart, C., Selvaraja, M., Leong, M. Y., & Tan, P. L. (2022). Plant as an alternative source of antifungals against Aspergillus infections: A review. Plants, 11(22), 3009.
  13. Masita Arip, Tan Li Fang, Maha Abdullah, Ramajayaraj, Mogana, R, Selvaraja, M*. (2022). Exploration of Omics based biomarkers for cervical cancer. Discovery Oncology.
  14. Arip, M., Yap, V.L.*, Rajagopal, M*., Selvaraja, M*., Dharmendra, K., and Chinnapan, S. (2022). Evidence-Based Management of Uterine Fibroids with Botanical Drugs-A Review. Frontiers in Pharmacology, 13 (878407): 1-15.
  15. Yap, V.L., Rajagopal, M., Dharmendra, K., Abdullah, M., Selvaraja, M*. (2022). Latest Evidence in the Pathogenesis of Uterine Fibroids. Current Trends in Biotechnology and Pharmacy.
  16. Tan, P.L*., Rajagopal, M*., Chinnapan, S., Selvaraja, M*., Leong, M.Y., Tan, L.F., Yap, V.L. (2022). Cosmetics MDPI. 9 (46), 1-14.
  17. Okechukwu, P. N., Sharma, M. N., Selvaraja, M. N., Nalweyiso, J. N., Balachandran, A. N., Chan, H. K. N., & Gaurav, A. N. (2022). A Peep into The Insulin Signaling Pathway of Palmatine: In Vitro, In Vivo & Ex‐Vivo. The FASEB Journal, 36.
  18. Malarvili Selvaraja, Chun Lai Too, Lay Kim Tan, Bee Tee Koay, Maha Abdullah, Anim Md Shah, Masita Arip, Syafinaz Amin Nordin. (2022). Lupus Science and Medicine. 9,1-14.
  19. Sasikala Chinnapan, Malarvili Selvaraja, Kok King Wen, Lai Sally, Fu Wai Kuang. (2022). Application of Nanobiotics approach against antibacterial resistance. International Journal of Applied Pharmaceutics.
  20. Pukar Khanal, Farshid Zargari, Bahar Farasati Far, Dharmendra Kumar, Mogana Rajagopal, Yasir K Mahdi, Najwan Jubair, Shailendra K. Saraf, Parveen Bansal, Ranjit Signh, Malarvili Selvaraja* and Yadu Nandan*. (2021). Intergration of System Biology tools to investigate Huperzine A as an anti-Alzheimer agent. Frontiers in Pharmacology (Section Neuroscience).
  21. Mun Yee Leong, R.Mogana, Malarvili Selvaraja, Sasikala Chinnapan, Choo Shiuan Por, Chuan Sheng Yap, Puay Luan Tan, Dharmendra K. (2021). A review on Herbal Skin Care creams. Current trends in Biotechnology and Pharmacy.
  22. Malarvili Selvaraja, Chin Voon Kin, Abdullah, M, Arip, M, Chin, V.K., Shah, A, Nordin, S.A. (2021). HLA_DRB1*04 as risk allele to systemic lupus erythematosus and lupus nephritis in the Malay population of Malaysia. Frontiers in Medicine (Nephrology).
  23. Malarvili Selvaraja, Abdullah, M, Arip, M, Chin, V.K., Shah, A, Nordin, S.A. (2019). Elevated Interleukin-25 and Its Association to Th2 Cytokines in Systemic Lupus Erythematosus with Lupus Nephritis. PLOS One 14(11): 1-17.
  24. Malarvili Selvaraja, Daud,C.K.D.C.K., Jalil, M.A., Shah,A.M., Nordin,S.A. Bajari, Z., Min, C.C., Abdullah, M. (2018). Screening Method for Potential Arthritic Autoantibodies in Systemic Lupus Erythematosus. Malaysian Journal of Medicine and Health Sciences under special edition: Updates in Clinical Laboratory and Experimental Medicine: 41-44.
  25. Malarvili Selvaraja, Abdullah, M., Shah, A., Arip, M., Nordin, S.A. (2017). Role of Cytokine IL-5 and IL-25 as biomarkers in systemic lupus erythematosu. Lupus Sci Med Vol 4, A141 –A142.
  26. Azhar,Y., Chiong, H.S., S. Malarvili1, M.N. Somchit and K.H.Yuen. (2009). Preliminary Ulcerogenic Evaluation of Piroxicam – Loaded Liposoms. Journal of Industrial Technology Vol. 19(1), ICINT, 1-16
  27. Malarvili A/P Selvaraja, Adolph William Ndyeabura, Gabriel Akyirem Akowuah, And Patrick N Okechukwu. (2011). Antidiabetic Activity of Crude Stem Extracts of Coscinium . 2010. Fenestratum on Streptozotocin-Induced Type-2 Diabetic Rats. Asian Journal of Pharmaceutical and Clinical Research Vol. 4 (4).
  28. Malarvili Selvarajah, Zakaria, Z.A., Long, K., Ahmad, Z., Yaacob, A., Sommchit. M.N. (2016). Anti-ulcerogenic activity of Virgin Coconut oil contributes to the stomach health of human kind. TANG [ HUMANITAS MEDICINE], Volume 6(2): Page 11.
  29. Malarvili Selvarajah, Ahmad,Z., Zakaria,Z.A., Siong,C.H., Kin, Y.Y, Long, K., Sommchit, M.N. (2016). Comparative Investigation into the anti-ulcer activity of virgin coconut oil and coconut oil in pylorous ligated animal model. TANG [ HUMANITAS MEDICINE], Volume 5. 4(28).
  30. Ahmad, Z., Zamhuri, K.F., Yaacob, A., Siong, C.H., Selvaraja, M., Ismail, A., Hakim, M.N. (2012). In Vitro anti-diabetic activities and chemical analysis of polypeptide-K and oil isolated from seeds of Momordica Charantia (Bitter Gourd). Molecules. 10; 17(8): 9631-40.
  31. Ang KP, Tan HK, Selvaraja M, Kadir AA, Somchit MN, Akim AM, Zakaria ZA, Ahmad Z. (2011). Cryptotanshinone attenuates in-vitro oxLDL-induced pre-lesional atherosclerotic events. Planta Medica, 77(16): 1782-1787.

Achievements & Awards

Malaysian Technology Expo 2023 – Merit Award

External international grant reviewer