VIRTUAL TOUR
Dr Michelle Teo Yee Mun
Lecturer | Department of Biotechnology
michelleteo@ucsiuniversity.edu.my
Academic Qualifications
PhD Science
MSc Biomedical Science
BSc (Hons) Biological Sciences
Areas of Interest
Molecular Oncology (Immunotoxins, Antibody Engineering)
Research Grants
- Name of grant: Malaysia Fundamental Research Grant Scheme
Funder: Ministry of Education
Project Title: Investigating the synergistic potential between a G12V/A mutated KRAS vaccine in combination with anti-PD-L1 checkpoint inhibitor against colorectal cancer
Code: FRGS/1/2021/STG01/UCSI/02/1
Duration: 3 years
Role: Co-investigator
Amount: RM 194,100
Status: On-going - Name of grant: Malaysia Fundamental Research Grant Scheme
Funder: Ministry of Education
Project Title: Investigating the potential of surface modified cyclodextrin based gold nanoparticles for cytotoxic drugs to enhance the apoptosis in cancer cell lines.
Code: FRGS/1/2021/SKK0/UCSI/02/5
Duration: 2 years
Role: Co-investigator
Amount: RM 100,108
Status: On-going - Name of grant: UCSI Research Excellence & Innovation Grant
Funder: UCSI University
Project Title: Preclinical assessment of hemi-synthesized juglone derivative for its anticancer effects on various solid tumours
Code: REIG-FAS-2020/030
Duration: 2 years
Role: Principal investigator
Amount: RM 50,000
Status: On-going - Name of grant: UCSI Research Excellence & Innovation Grant
Funder: UCSI University
Project Title: Immuno-engineering and evaluation of an orally administered mutated KRAS multivalent tandem vaccine against colorectal cancer.
Code: REIG-FAS-2020/060
Duration: 2 years
Role: Co-investigator
Amount: RM 50,000
Status: On-going
Current Research Project
- Preclinical assessment of a hemisynthesized curcumin derivatives for its anticancer effects on various solid tumours
- In vivo prophylactic and therapeutic study of KRAS mimotope vaccine (G12V/G12A) in combination with checkpoint inhibitor and its pairing with a KRAS aptamer-based biosensor
Publications
- Michelle Yee Mun Teo, Jung Yin Fong, Wan Ming Lim and Lionel Lian Aun In, (2021) Current advances and trends in KRAS targeted therapies for colorectal cancer. Molecular Cancer Therapeutics. 20, 30-44; DOI 10.1158/1541-7786.MCR-21-0248.
- Michelle Yee Mun Teo, Jeremy Jeack Ceen Ng, Jung Yin Fong, Jung Shan Hwang, Adelene Ai Lian Song, Renee Lay Hong Lim and Lionel Lian Aun In, (2021) Development of a single-chain fragment variable fused-mutant HALT-1 recombinant immunotoxin against G12V mutated KRAS colorectal cancer cells. PeerJ, 9:e11063; DOI 10.7717/peerj.11063.
- Teng Jia Ng, Michelle Yee Mun Teo, Dek Shen Liew, Paul Etim Effiong, Jung Shan Hwang, Crystale Siew Ying Lim and Lionel Lian Aun In, (2019), Cytotoxic and apoptosis-inducing effects of wildtype and mutated Hydra actinoporin-like toxin 1 (HALT-1) on various cancer cell lines. PeerJ, 7:e6639; DOI 10.7717/peerj.6639.
- Allan Wee Ren Ng, Pei Jun Tan, Winfrey Pui Yee Hoo, Dek Sen Liew, Michelle Yee Mun Teo, Pui Yan Siak, Sze Man Ng, Ee Wern Tan, Raha Abdul Rahim, Renee Lay Hong Lim, Adelene Ai Lian Song and Lionel Lian Aun In, (2018), In silico-guided sequence modifications of K-ras epitopes improve immunological outcome against G12V and G13D mutant KRAS antigens. PeerJ, 6:e5056; DOI 10.7717/peerj.5056.
- Michelle Yee Mun Teo, Jung Shan Hwang, Adelene Ai Lian Song, Renee Lay Hong Lim and Lionel Lian Aun In, (2019) Immuno-engineering and development of anti-mKRAS G12V single-chain variable fragment (scFv) fused-mHALT-1 recombinant immunotoxins against KRAS-positive colorectal cancer cells. BMC Proceedings, 13(8), 10; DOI 10.1186/s12919-019-0169-6.
Awards and Recognitions
- Best Presenter Award – 4th International Conference on Molecular Biology and Biotechnology (ICMBB) 2021
- Finalist - The Falling Walls lab AIMST, Malaysia
- Best Abstract Award - Hong Kong Croucher Summer Course 2018
- Best Poster Award - 2nd International Conference on Molecular Biology and Biotechnology (ICMBB) 2017
